Data from: Black Queen evolution and trophic interactions determine plasmid survival after the disruption of conjugation network

dc.contributor.affiliationUniversity of Helsinki - Cairns, Johannes
dc.contributor.affiliationUniversity of Jyväskylä - Koskinen, Katariina
dc.contributor.affiliationUniversity of Jyväskylä - Penttinen, Reetta
dc.contributor.affiliationUniversity of Jyväskylä - Patinen, Tommi
dc.contributor.affiliationUniversity of Helsinki - Hartikainen, Anna
dc.contributor.affiliationUniversity of Helsinki - Jokela, Roosa
dc.contributor.affiliationUniversity of Helsinki - Ruusulehto, Liisa
dc.contributor.affiliationUniversity of Helsinki - Viitamäki, Sirja
dc.contributor.affiliationUniversity of Jyväskylä - Mattila, Sari
dc.contributor.affiliationUniversity of Helsinki - Hiltunen, Teppo
dc.contributor.affiliationUniversity of Jyväskylä - Jalasvuori, Matti
dc.contributor.authorCairns, Johannes
dc.contributor.authorKoskinen, Katariina
dc.contributor.authorPenttinen, Reetta
dc.contributor.authorPatinen, Tommi
dc.contributor.authorHartikainen, Anna
dc.contributor.authorJokela, Roosa
dc.contributor.authorRuusulehto, Liisa
dc.contributor.authorViitamäki, Sirja
dc.contributor.authorMattila, Sari
dc.contributor.authorHiltunen, Teppo
dc.contributor.authorJalasvuori, Matti
dc.date.accessioned2025-03-24T15:11:25Z
dc.date.issued2019-08-09
dc.date.issued2019-08-09
dc.descriptionMobile genetic elements such as conjugative plasmids are responsible for antibiotic resistant phenotypes in many bacterial pathogens. The ability to conjugate, the presence of antibiotics and ecological interactions all have a notable role in the persistence of plasmids in bacterial populations. Here, we set out to investigate the contribution of these factors when the conjugation network was disturbed by a plasmid-dependent bacteriophage. Phage alone effectively caused the population to lose plasmids, thus rendering them susceptible to antibiotics. Leakiness of the antibiotic resistance mechanism allowing Black Queen evolution (i.e. race to the bottom) was a more significant factor over antibiotic concentration (lethal vs sub-lethal) in determining plasmid prevalence. Interestingly, plasmid loss was also prevented by protozoan predation. These results show that the outcome of attempts to re-sensitize bacterial communities by disrupting the conjugation network are highly dependent on ecological factors and resistance mechanisms.
dc.identifierhttps://doi.org/10.5061/dryad.10gk660
dc.identifier.urihttps://hydatakatalogi-test-24.it.helsinki.fi/handle/123456789/9171
dc.rightsOpen
dc.rights.licensecc-zero
dc.subjectTetrahymena thermophila
dc.subjectconjugation
dc.subjectblack queen evolution
dc.titleData from: Black Queen evolution and trophic interactions determine plasmid survival after the disruption of conjugation network
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