Data from: Maternal antibodies contribute to sex based difference in hantavirus transmission dynamics

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dc.contributor.affiliationUniversity of Jyväskylä - Kallio, Eva R.
dc.contributor.affiliationForest Research Institute - Henttonen, Heikki
dc.contributor.affiliationUniversity of Jyväskylä - Koskela, Esa
dc.contributor.affiliationUppsala University - Lundkvist, Åke
dc.contributor.affiliationUniversity of Jyväskylä - Mappes, Tapio
dc.contributor.affiliationUniversity of Helsinki - Vapalahti, Olli
dc.contributor.affiliationUppsala University - Lundkvist, A.
dc.contributor.authorKallio, Eva R.
dc.contributor.authorHenttonen, Heikki
dc.contributor.authorKoskela, Esa
dc.contributor.authorLundkvist, Åke
dc.contributor.authorMappes, Tapio
dc.contributor.authorVapalahti, Olli
dc.contributor.authorLundkvist, A.
dc.date.accessioned2025-03-24T15:21:28Z
dc.date.issued2014-11-21
dc.date.issued2014-11-21
dc.descriptionIndividuals often differ in their ability to transmit disease and identifying key individuals for transmission is a major issue in epidemiology. Male hosts are often thought to be more important than females for parasite transmission and persistence. However, the role of infectious females, particularly the transient immunity provided to offspring through maternal antibodies (MatAbs), has been neglected in discussions about sex-biased infection transmission. We examined the effect of host sex upon infection dynamics of zoonotic Puumala hantavirus (PUUV) in semi-natural, experimental populations of bank vole (Myodes glareolus). Populations were founded with either females or males that were infected with PUUV while the other sex was immunized against PUUV infection. The likelihood of the next generation being infected was lower when the infected founders were females, underlying the putative importance of adult males in PUUV transmission and persistence in host populations. However, we show that this effect likely results from transient immunity that infected females provide to their offspring, rather than any sex-biased transmission efficiency per se. Our study proposes a potential contrasting nature of female and male hosts in the transmission dynamics of hantaviruses.
dc.identifierhttps://doi.org/10.5061/dryad.d632k
dc.identifier.urihttps://hydatakatalogi-test-24.it.helsinki.fi/handle/123456789/10918
dc.rightsOpen
dc.rights.licensecc-zero
dc.subjecttransmission
dc.subjectbank vole
dc.subjectmaternal antibody
dc.subjectHost sex
dc.subjectPuumala hantavirus
dc.titleData from: Maternal antibodies contribute to sex based difference in hantavirus transmission dynamics
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